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Biofreeze is the Number 1 recommended topical pain reliever by hands-on healthcare professionals. Biofreeze products use the cooling effect of menthol, a natural pain reliever, which penetrates quickly to sooth minor muscle and joint pain. Biofreeze products help manage discomfort by offering a variety of benefits that assist in therapy, pain relief, exercise, training and overall comfort. Long lasting pain relief for up to 4 hours.